Fig. 9: IL-11 expression is correlated with progression of human cancers. | Nature Communications

Fig. 9: IL-11 expression is correlated with progression of human cancers.

From: Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

Fig. 9

a–c Adenomas (n = 11) and early (n = 10) and advanced (n = 10) colorectal cancers were stained with anti-IL-11 antibody (a). Representative staining of the respective tumors and adjacent normal tissues. Scale bars, 100 μm. IL-11+ area and total area were calculated and the percentages of IL-11+ area per area are plotted (b). The intensities of IL-11+ signals and total area were calculated and intensities of IL-11+ per area are expressed as arbitrary units (a.u.) (c). Results are mean ± SEM. n = 11 (adenoma), 10 (early cancer), 8 (nontumor, advanced cancer), or 10 (tumor, advanced cancer). Scale bars, 100 μm. Statistical significance was determined using the two-sided Mann–Whitney U test (b, c). Source data are provided as a Source Data file.

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