Fig. 4: Comparison of expression and cell-type-specific loading of miRNAs. | Nature Communications

Fig. 4: Comparison of expression and cell-type-specific loading of miRNAs.

From: Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading

Fig. 4

a Read counts per million in individual AGO- and cell-type-specific libraries for miR-75 showing intestine enrichment. Live animal image (right) of the promoter of miR-75 fused to GFP, showing tight correlation of expression with loading profile. b Cell-type-specific read counts and promoter GFP fusion for neuron-enriched miR-90. c Cell-type-specific read counts and promoter GFP fusion for muscle-specific miR-67. d Intestine-specific loading of miR-239a shown by read counts in individual cell-type libraries. Promoter expression of miR-239a showing enrichment of fluorescence in neurons. e Intestine-enriched loading of miR-83 as compared to neuron-enriched expression. Graphs show reads per million in indicated cell types of two biological replicate experiments, two bars. Scale bars, 50 µm.

Back to article page