Fig. 5: Discovery and detection of non-reference miRNAs.

a Volcano plot showing all non-reference miRNAs enriched (log2 fold change > 2, FDR < 0.05 relative to wild type). b Table showing abundance (reads per million, RPM) and number of unique sequences (# unique) which make up each class of reference miRNA, novel candidate miRNA or isomiR (nucleotide shift or substitution).