Fig. 3: Three respiratory infections associated with gut microbiome composition in African buffalo based on canonical correspondence analysis: Mycoplasma bovis (MB), bovine viral diarrhea virus (BVDV), and bovine herpesvirus (BHV).
From: Diet and gut microbiome enterotype are associated at the population level in African buffalo

Differences in the magnitude and/or direction of association between disease and the microbiome were observed between the restricted regime and the hay/green vegetation regime based on visualization and envfit analysis of principal coordinate analysis. This plot shows differences in microbiome community composition associated with infection status based on principal coordinate analysis of Bray–Curtis distances for the restricted and hay/green vegetation regimes. Analysis by envfit was based on 134 samples in the restricted regime (5 MB positive, 35 BVDV positive, 85 BHV positive) and 177 samples in the hay/green vegetation regime (10 MB positive, 48 BVDV positive, 159 BHV positive) for which complete disease datasets were available. p-values for envfit analysis of infections within each group are shown on each panel. Colored points indicate seroconversion (M. bovis, positive = red) or presence (BVDV, positive = blue; BHV, positive = yellow), and gray points indicate lack of seroconversion (M. bovis) or absence (BVDV and BHV). Small points indicate individual samples, and larger circles indicate the means for infected and uninfected groups. Source data are provided as a Source Data file.