Fig. 4: Organotropism of mutations in advanced breast cancer.
From: Genomic profile of advanced breast cancer in circulating tumour DNA
a Association of mutations in indicated genes with sites of metastasis. p-values from false discovery corrected two-sided Fisher’s exact test (ESR1: bone q < 0.0001, liver q < 0.0001, lymph node q = 0.0001; GATA3: bone q = 0.0009; PIK3CA: lymph node q = 0.005; TP53: lymph node q = 0.002, liver q = 0.002, bone q = 0.02). b Association of mutations in indicated genes with sites of metastasis in left HR + HER2- and right TNBC. p-values from false discovery corrected two-sided Fisher’s exact test (HR + HER2- ESR1: liver q = 0.004, bone q = 0.02).
