Fig. 7: Correlations among FUT8 and B7H3 expression in TNBC tissues.

a Expression of FUT8 protein in 14 representative human TNBC fresh samples by immunoblot. N, matched normal tissue; T, tumor tissue. b The representative intensity images for each IHC score of FUT8 staining in TNBC tumor tissues were shown (left). Kaplan–Meier plots of the overall survival of patients, stratified by protein expression of FUT8 (right). The p value was assessed using the log-rank test (two-sided). c The representative images for B7H3 staining in two patients with FUT8 expression (left). Case 1 showed low expression of FUT8 with low expression of B7H3. Case 2 showed high expression of FUT8 with high expression of B7H3. The correlation of B7H3 with FUT8 expression status in TNBC patient tumors (right). The relationship was assessed using Pearson’s chi-square test. d Kaplan–Meier plots of the overall survival of patients, stratified by protein expression of both B7H3 and FUT8. The p value was assessed using the log-rank test and further corrected with the Benjamini–Hochberg method (two-sided).