Fig. 4: In vitro NIR-II fluorescence imaging of PCP-BDP2 NPs.
From: J-aggregates of meso-[2.2]paracyclophanyl-BODIPY dye for NIR-II imaging
a NIR-II fluorescence images of different concentrations. Scale bar, 5 mm. b The quantitative relationship between NIR-II fluorescence intensity with concentrations. Bars represent mean ± SD derived from n = 3 independent experiments. c Comparison of penetration depth of PCP-BDP2 NPs and ICG (1 mg/mL, 1100 nm LP filter, 500 ms) under the different thickness of chicken tissue. Scale bar, 5 mm. NIR-II fluorescence imaging of blood vessels in d brain and e hindlimb of PCP-BDP2 NPs and ICG, respectively. f, g The quantification of fluorescent signals at the cross-section in hindlimb and brain (along the red-dashed line), respectively. The results are representative of three independent experiments. Source data underlying (b, f, g) are provided as a Source data file.
