Table 2 Details of epidemiological clusters defined within the S. sonnei population.

From: Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

New genotyping framework

 

Previously defined as

 

Description

Genotype

Name

Name

Study

 

Lineage II

 2.8

Korea II

Korea II

Holt 2012

Associated with Korea

 2.9, 2.10, 2.11

Latin America II

South America II

LA sublineage IIa & IIb

Holt 2012

Baker 2017

Associated with Latin America

Lineage III

 3.4

Latin America III

South America III

LA sublineage IIIa & IIIb

Holt 2012

Baker 2017

Associated with Latin America

 3.6

Central Asia III

Central Asia IIIa

Holt 2012

Associated with Central Asia

 3.6.1

CipR parent

This study

Subclade from which ciprofloxacin-resistant sublineage emerged

 3.6.1.1

CipR

Ciprofloxacin-resistant

Pop2

The 2015

The 2019

Ciprofloxacin-resistant triple mutation sublineage

 3.6.1.1.1

CipR.SEA

-

This study

Ciprofloxacin-resistant isolates associated with South East Asia

 3.6.1.1.3.1

CipR.MSM1

MSM clade 1

Baker 2018

MSM-linked ciprofloxacin resistant isolates

 3.6.1.1.2

CipR.MSM5

BAPS1

MSM Clade 5

Ingle 2019

Bardsley 2020

MSM-linked ciprofloxacin resistant isolates

 3.7.25

MSM4

MSM Clade 4

Baker 2018

MSM-linked

 3.7.29

Vietnam III

VN clone

Holt 2012

Associated with South East Asia

 3.7.29.1

VN2

VN clone, sweep 2

Holt 2013

Clonal group originating from genetic sweep 2

 3.7.29.1.1

VN3

VN clone, sweep 3

Holt 2013

Clonal group originating from genetic sweep 3

 3.7.29.1.1.1

VN3.KH2

KH2

Holt 2013

Kanh Hoa subclone 2, emerging from sweep 3

 3.7.29.1.1.2

VN4

VN clone, sweep 4

Holt 2013

Clonal group originating from genetic sweep 4

 3.7.29.1.2

VN2.MSM2

MSM Clade 2

Bardsley 2020

MSM-linked strains, emerging from sweep 2

 3.7.29.1.2.1

VN2.MSM2.Aus

-

(part of BAPS3)

This study

Ingle 2019

Australian MSM-linked, emerging from sweep 2

 3.7.29.1.3

VN2.Hue

Hue2

Holt 2013

Hue subclone 2, emerging from sweep 3

 3.7.29.1.4

VN2.KH1

KH1

Holt 2013

Kanh Hoa subclone 1, emerging from sweep 2

 3.7.29.1.4.1

VN2.KH1.Aus

-

(part of BAPS3)

This study

Ingle 2019

Australian isolates, emerging from KH1

 3.7.30

Middle East III

Middle East III

Holt 2012

Associated with Middle East

 3.7.30.4

Israel III

Israel III

This study

Associated with Israel

 3.7.30.4.1

OJC

OJC-associated

Baker 2016

Associated with the Orthodox Jewish communities in Israel, UK, USA and Europe