Fig. 6: Central and peripheral nervous system (CNS and PNS) myelin. | Nature Communications

Fig. 6: Central and peripheral nervous system (CNS and PNS) myelin.

From: Nanostructure-specific X-ray tomography reveals myelin levels, integrity and axon orientations in mouse and human nervous tissue

Fig. 6

a Oligodendrocyte- and Schwann cell-produced myelin in CNS and PNS, respectively. Trigeminal nerve shown in yellow in the mouse head scheme. Sketches created with BioRender.com. b Extracting the myelin-specific signal from intensity vs. q plots, from a scattering pattern including both CNS and PNS peaks (arrows). Top curves: blue → raw data, orange → first fit, yellow → second fit. Bottom curve: myelin signal. Colored areas: identified CNS and PNS peaks used for further analysis. c CNS (magenta) and PNS (green) mapping in side- and top-projections, and combined image. Arrows: white → severed brainstem PNS nerves, orange → proximal trigeminal nerves. d CNS and PNS 3D myelin maps, showing the ball-socket CNS-PNS fit at the trigeminal nucleus.

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