Fig. 3: Parasitemia during immunization phase. | Nature Communications

Fig. 3: Parasitemia during immunization phase.

From: Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial

Fig. 3

a Parasitemia (parasites/ml) was estimated by quantitative PCR during the immunization phase after immunizations 1, 2, and 3. Individual parasitemia levels are shown. Red circles: vaccinated group (protected); turquoise triangles: vaccinated group (unprotected). During the first vaccination period, one unprotected vaccinee missed visits of Study days 9 and 10 after immunization, two volunteers missed the visit on Study day 10 after immunization. At second immunization, one protected volunteer missed the visit on Study day 15. For the third immunization, one unprotected and one protected vaccinee missed the visit on Study day 38 after immunization. b Number of subjects positive per number injected, median peak parasite density among positives, and study day of median peak parasite density among positives after each dose of PfSPZ-CVac. Values are given for all vaccinated volunteers as well as separated by outcome of CHMI.

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