Fig. 5: Structures of WNVKUN and bMVEV highlight features involved in neurovirulence and immunogenicity. | Nature Communications

Fig. 5: Structures of WNVKUN and bMVEV highlight features involved in neurovirulence and immunogenicity.

From: A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

Fig. 5

A dimer of E–M heterodimers coloured according to the domain: DI, red; DII, yellow; DIII, blue; membrane domain, purple: and M, pink. Boxes highlight the regions of interest. a Comparison of the backbone and sequence alignment of flavivirus structures near the Asn154 site. Structures are coloured in accordance with the sequence alignment and displayed as a wall-eye stereo view. b Comparison of the dimer interface between WNVKUN (orange, top), bMVEV (blue, middle) and JEV (green, bottom, PDB: 5WSN). Chains are labelled with the protein name and domain. Distances are shown for hydrogen bonds.

Back to article page