Fig. 6: Recognition of WNVKUN and bMVEV by monoclonal antibody E16. | Nature Communications

Fig. 6: Recognition of WNVKUN and bMVEV by monoclonal antibody E16.

From: A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

Fig. 6

a E16 binding is virus-specific with no recognition of MVEV- or bMVEV-infected cells observed at 1 µg/mL. The bar graph represents the average OD from two technical replicates. b Structure of the WNV complex with E16 (left, PDB: 1ZTX) is compared to models of the bWNVKUN-E16 (middle) and bMVEV-E16 complex (right). The structures of bWNVKUN and bMVEV were aligned to WNV without minimization of either component. Red lines indicate clashes.

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