Fig. 6: D614G and the accompanying mutations on structure remodeling.
From: The architecture of the SARS-CoV-2 RNA genome inside virion
a Line plot showing the point mutation resided regions tend to form local interactions. The C241U, C3037U, C14408U, and A23403G (D614G) mutants are marked as solid lines. b The A-to-G transition (D614G mutant) at 23,403 nt remodels two bulge structures into a single six-nucleotide bulge. Red stars mark the mutated nucleotides. ΔG, free energy. c–e The D614G accompanying mutations have no influence on duplexes except for the C14408U transition (e).
