Fig. 1: Advanced NSCLC single-cell atlas.

a Graph illustration of the baseline information of the 42 patients, including subtypes, stages, mutation status, and smoking history. b UMAP plot of 90,406 cells from 42 patients, colored by their 11 major cell types. c Heatmap of canonical cell-type markers of 11 major cell types. d UMAP plot of all cells, colored by patients. e Major cell-type composition of each patient. Biopsies were all taken from the primary lung tumors. Source data are provided as a Source Data file.