Fig. 7: Modeling tACS stimulation to both PY and FS Cells. | Nature Communications

Fig. 7: Modeling tACS stimulation to both PY and FS Cells.

From: Transcranial alternating current stimulation entrains alpha oscillations by preferential phase synchronization of fast-spiking cortical neurons to stimulation waveform

Fig. 7

Phase-locking (top) and firing rate (bottom) response to tACS applied to both the PY and FS cells. Each pixel in the histogram represents five seconds of simulation with the appropriate amplitude tACS stimulation. In the plot, tACS amplitude and frequency range from 0 to 10 pA and 0 to 30 Hz, respectively. The FS neurons exhibit two Arnold tongues, the first centered around the endogenous frequency for the PY neurons, 13.5 Hz, and the second centered at the first harmonic. For PY neurons, an Arnold tongue is also present at the endogenous frequency. Phase-locking for the FS neurons is high compared to the model where FS neurons were not stimulated, especially at the first harmonic. In this plot, the high phase-locking in the FS neurons overshadows the Arnold tongue in the PY neurons, but it is still present.

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