Fig. 3: Comparison of representative motif models from Rosetta-SWM, refinement of Rosetta-SWM models and base-pair-restrained prediction by BRiQ. | Nature Communications

Fig. 3: Comparison of representative motif models from Rosetta-SWM, refinement of Rosetta-SWM models and base-pair-restrained prediction by BRiQ.

From: Pairing a high-resolution statistical potential with a nucleobase-centric sampling algorithm for improving RNA model refinement

Fig. 3

Energy versus RMSD values of the conformations sampled by (i) Rosetta-SWM, (ii) refinement of Rosetta-SWM conformations by BRiQ, (iii) structure prediction by BRiQ with all native base pairs fixed for A CG-helix, B GCAA-tetra loop, C UUCG-tetra loop, D j55a-P4P6-fixed, and E loopE-fixed. Structure alignment of native (blue) to the best in top 1% predicted models by Rosetta-SWM (panel iv) and BRiQ refinement (panel v) in the bottom panel.

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