Fig. 4: Potential transcription factors binding sites (A-box, E-box, and HRE) identified by ATAC-seq peak. | Nature Communications

Fig. 4: Potential transcription factors binding sites (A-box, E-box, and HRE) identified by ATAC-seq peak.

From: Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals

Fig. 4

A 72 bp region (green box) was used for dual-luciferase assays. Gene structure of cgILP is shown in the top bars, where purple bars indicate exons, and arrows along the line indicate transcriptional orientation. The ATAC-seq peaks are not direct extrapolation of the regions with the highest sequencing signal as the calling process takes into account both replicates, the averaged background over a window, and the shift induced by the library construction process.

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