Table 1 Particle size, polydispersity index (PDI), and ζ-potential of PLGA micro- and nanoparticles.

From: PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy

Vaccine compound

Size (nm ± SD)

PDI ± SD

ζ potential (mV ± SD)

MP-OVA/polyI:C

1377 ± 62.07

0.256 ± 0.102

−47.3 ± 1.02

MP-OVA/Riboxxim

1437 ± 162.9

0.396 ± 0.129

−51.0 ± 2.85

MP Empty

1436 ± 235.2

0.385 ± 0.172

−56.0 ± 0.608

NP OVA/Riboxxim

240.4 ± 24.56

0.407 ± 0.128

−30.2 ± 0.692

  1. Results are expressed as means ± SD. For each compound, at least three independent batches were prepared. Measurement was performed in triplicates (n = 3).
  2. MP microparticles, NP nanoparticles, SD standard deviation, PDI polydispersity index.
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