Fig. 4: Yields for photoreductive coupling of aldehydes and ketones over MFM-300(Cr). | Nature Communications

Fig. 4: Yields for photoreductive coupling of aldehydes and ketones over MFM-300(Cr).

From: Construction of C-C bonds via photoreductive coupling of ketones and aldehydes in the metal-organic-framework MFM-300(Cr)

Fig. 4

The yields of corresponding diols are listed under the chemical structure for each substrate, and these were determined by NMR spectroscopic analysis of the reaction mixture using an internal standard (details are given in the Supplementary Information). The data for reaction conversion and yields of by-product (if any) are also given in the Supplementary Information. Reaction conditions: substrate (0.50 mmol), MFM-300(Cr) (10%, 0.05 mmol), CH3CN/H2O (15 mL/15 mL), Na2SO3 (0.25 M), 25 °C, 350–780 nm. The reaction time is 24 h unless noted as a36-48 h or b12 h. For comparison, the yields of the same reaction from experiments reported in the literature are given below in brackets. In red9: [IrI(FCF3ppy)2(bpy)](PF6) (1 mol%), NBu3 (3 equiv), DMF, 450 nm, RT, 15 h; in blue14: Pt(II) complex (1 mol%), DIPEA (diisopropylethylamine, 2 equiv), DMF, >370 nm, 6 h; in purple13: Cu(pypzs)(BINAP)BF4 (2 mol%), Hantzsch ester (2 equiv.), THF, blue LED, 18 h; in green60: (t-BuO)3FeK (0.05 eq), Mg, SiR3Cl (1.5 eq), THF, RT, 12 h.

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