Fig. 5: Enzymatic modular synthesis of core 2 O-GalNAc glycans. | Nature Communications

Fig. 5: Enzymatic modular synthesis of core 2 O-GalNAc glycans.

From: Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics

Fig. 5

G1: β1-4 galactosylation with NmLgtB and UDP-Gal; G3: α1-3 galactosylation with Bα3GalT and UDP-Gal; S1: α2-3 sialylation with PmST1-M144D, NmCSS, CTP, and Neu5Ac; S3: α2-6 sialylation with Pd2,6ST, NmCSS, CTP, and Neu5Ac; N1: β1-4 N-acetylgalactosaminylation with CjCgtA and UDP-GalNAc; F1: α1-2 fucosylation with Hm2FT and GDP-Fuc; F2: α1-3 fucosylation with Hp3FT and GDP-Fuc. SF, Fmoc protected Ser.

Back to article page