Fig. 2: Levels of unconjugated and conjugated bile acids in the cecal content of Il10−/− mice at the time of sacrifice where experimental colitis was induced by inoculation with Escherichia coli LF82 (E), Enterococcus faecalis OG1RF (E), and Ruminococcus gnavus ATCC29149 (R).

Gnotobiotic Il10−/− mice were inoculated with GUT-103 (N = 5), EER (N = 9), GUT-103 plus EER (preventive protocol) (N = 7), and EER plus GUT-103 (therapeutic protocol) (N = 7). Il10−/− mice were inoculated via gavage with GUT-103 (2 × 10+7 cfu/strain) or EER (2 × 10+7 cfu/strain). a Unconjugated bile acids: αMCA α-muricholic acid, βMCA β-muricholic acid, CA cholic acid, CDCA chenodeoxycholic acid, LCA lithocholic acid, UDCA ursodeoxycholic acid, DCA deoxycholic acid. b Conjugated bile acids: TβMCA taurine-conjugated β-muricholic acid, TCA taurocholic acid, TCDCA taurochenodeoxycholic acid, TUDCA tauroursodeoxycholic acid, GUDCA glycoursodeoxycholic acid, GCA glycine-conjugated cholic acid, GLCA glycine-conjugated lithocholic acid. 1e-way ANOVA, Mean ± SE, *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001. Source data and calculated P-values are provided as a Source Data file.