Fig. 1: Divergent and modular assembly of fluorogenic probes via Earth-abundant manganese(I)-catalyzed C–H activation.
From: Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
a A versatile approach towards diverse fluorogenic probes. b Selected optimization findings for the utilization of bromoalkyne B1 and terminal alkyne B2 to furnish linear alkynylated and bent alkenylated BODIPY amino acid imaging probes. 2-py, 2-pyridyl; SAR, structure–activity relationship; (1-Ad)CO2H, 1-adamantanecarboxylic acid; DCE, 1,2-dichloroethane; PivOH, pivalic acid.
