Fig. 1: Study overview.

We started with a search in the Gene Expression Omnibus. Manual examination of the studies and a set of filters resulted in 43 studies that had whole-genome expression profiles from blood and muscle. The data covered 59 exercise cohorts that were partitioned into four types of meta-analysis (i.e., by tissue and exercise modality). Seven-hundred and thirty-nine subjects were included in total, where some are represented in several cohorts, for example when sampling was made in association to both acute exercise and long-term training.