Fig. 1: Copper-catalyzed carbo-difluoromethylation of alkenes could enable modular synthesis of complex alkyl-difluoromethanes.
From: Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay

a Complex alkyl-difluoromethanes as pharmaceuticals. b A state-of-the-art method for the synthesis of alkyl-difluoromethanes. c Copper-catalyzed carbo-difluoromethylaton of alkenes.