Fig. 3: The T-elements comprise conserved homeodomain binding sites and a novel shared motif.
From: Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers
a Schematic of the TAAR cluster showing relative positions of TE1 and TE2 (magenta). Genes are indicated by gray boxes. Schematic of the T-elements (bottom) showing placement of phylogenetically conserved HD sites (purple triangles). The T-elements also contain a highly conserved, shared homology, the SHiTE motif (red diamonds). b Schematic of known functional OR enhancers showing positions of conserved HD sites. c Alignments of segments of TE1 and TE2 from 16 mammalian species showing all conserved HD sites, HD1-4 in each. d Alignment of the TE1 and TE2 shared homology (SHiTE) motifs across representative mammalian species. Single alignment is split, top (TE1) and bottom (TE2).
