Table 1 Descriptive of the participated cohorts (N = 16,265).
From: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
Cohort | N | Age (year) Mean ± SD | Female Percent | BMI (kg/m2) Mean ± SD | Percent on Lipid meds | HDL (mg/dl) Mean ± SD | LDL (mg/dl) Mean ± SD | TG (mg/dl) Mean ± SD |
|---|---|---|---|---|---|---|---|---|
European (N = 11,114) | ||||||||
Amish | 158 | 43.8 ± 13.2 | 54 | 27.8 ± 4.7 | 0 | 55.8 ± 14.9 | 139.5 ± 39.9 | 74.1 ± 39.4 |
BHS | 676 | 42.8 ± 4.5 | 55 | 29.9 ± 6.7 | 12 | 45.5 ± 13.2 | 126.7 ± 34.2 | 142.4 ± 92.9 |
CHS | 186 | 76.0 ± 5.0 | 55 | 27.1 ± 5.0 | 5 | 51.7 ± 13.5 | 117.1 ± 36.4 | 155.8 ± 82.0 |
FHS* | 2,648 | 66.4 ± 8.9 | 54 | 28.3 ± 5.3 | 44 | 57.3 ± 18.0 | 104.6 ± 31.4 | 118.9 ± 69.8 |
GOLDN* | 714 | 48.5 ± 15.9 | 50 | 28.5 ± 5.5 | 0 | 46.1 ± 13.0 | 123.8 ± 31.5 | 137.4 ± 85.8 |
KORA F4 | 1,651 | 61.0 ± 8.9 | 51 | 28.1 ± 4.8 | 16 | 56.5 ± 14.7 | 140.3 ± 35.3 | 129.9 ± 77.8 |
NAS | 674 | 72.4 ± 6.8 | 0 | 28.0 ± 4.1 | 36 | 49.3 ± 12.9 | 120.1 ± 33.0 | 137.7 ± 84.0 |
PIVUS | 963 | 70.1 ± 0.15 | 50 | 27.0 ± 4.3 | 16 | 58.6 ± 16.4 | 128.9 ± 33.9 | 112.6 ± 51.4 |
RS | 724 | 59.9 ± 8.2 | 54 | 27.5 ± 4.8 | 26 | 54.3 ± 15.9 | 134.7 ± 37.6 | 131.5 ± 76.0 |
TwinsUK* | 708 | 58.1 ± 9.3 | 100 | 26.6 ± 4.8 | 16 | 71.3 ± 17.8 | 123.9 ± 38.9 | 99.5 ± 52.1 |
WHI-BA23 | 940 | 68.3 ± 6.25 | 100 | 28.8 ± 5.9 | 14 | 51.0 ± 12.3 | 142.7 ± 37.6 | 154.0 ± 35.5 |
WHI-EMPC | 1,072 | 64.7 ± 7.1 | 100 | 28.8 ± 5.8 | 10 | 59.2 ± 15.8 | 133.0 ± 34.1 | 158.6 ± 80.1 |
African (N = 4,452) | ||||||||
ARIC | 1,877 | 56.5 ± 5.9 | 64 | 30.0 ± 6.2 | 8 | 53.4 ± 17.0 | 134.7 ± 38.8 | 112.1 ± 57.3 |
BHS | 282 | 42.7 ± 4.7 | 61 | 32.6 ± 8.7 | 7 | 49.6 ± 14.5 | 120.8 ± 33.9 | 114.8 ± 76.9 |
CHS | 189 | 73.0 ± 5.5 | 67 | 28.8 ± 5.0 | 4 | 59.3 ± 16.5 | 124.2 ± 34.7 | 114.6 ± 58.6 |
GENOA* | 315 | 61.1 ± 7.6 | 73 | 31.0 ± 6.3 | 6 | 56.9 ± 17.4 | 125.2 ± 41.4 | 136.1 ± 63.6 |
HyperGEN | 604 | 48.4 ± 11.2 | 67 | 32.5 ± 8.2 | 5 | 53.6 ± 15.0 | 122.6 ± 38.0 | 107.8 ± 62.5 |
WHI-BA23 | 652 | 62.8 ± 6.6 | 100 | 31.9 ± 6.8 | 17 | 54.8 ± 14.6 | 152.6 ± 43.8 | 122.6 ± 81.3 |
WHI-EMPC | 533 | 62.7 ± 6.9 | 100 | 31.5 ± 6.1 | 10 | 58.1 ± 14.7 | 135.9 ± 37.9 | 119.6 ± 54.3 |
Hispanic (N = 699) | ||||||||
WHI-BA23 | 389 | 62.2 ± 6.9 | 100 | 29.6 ± 5.4 | 16 | 50.6 ± 13.2 | 142.7 ± 37.6 | 168.5 ± 95.6 |
WHI-EMPC | 310 | 61.6 ± 6.2 | 100 | 29.6 ± 5.3 | 11 | 54.7 ± 12.9 | 128.8 ± 35.1 | 162.7 ± 77.1 |
