Fig. 6: Effect of the complex anion on potency and selectivity. | Nature Communications

Fig. 6: Effect of the complex anion on potency and selectivity.

From: Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties

Fig. 6

a The effect of various anions on the potency of the Zn2+ complex; this is expressed as relative potency which is defined as the IC50 of [L2Zn3(PO4)]3+, [L2Zn3 (SO4)]4+ or [L2Zn3(O3POPh)]4+ divided by the IC50 of [L2Zn3]6+ (values <1 and >1 indicate increased and decreased potency respectively). b Effects of the anion on selectivity; these results are expressed as relative SI defined as the SI of [L2Zn3(PO4)]3+, [L2Zn3(SO4)]4+ or [L2Zn3(O3POPh)]4+ divided by the SI of [L2Zn3]6+ (values >1 and <1 indicate increased and decreased selectivity respectively).

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