Table 2 Multivariate analysis of the association of APCS SNPs with the risk of IPA among transplant recipients.

From: Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

Genetic/clinical variables

Adjusted HRa (95% CI)

P-value

Donor AA genotype in rs3753869

3.59 (1.54–8.78)

0.012

Unrelated donor

1.98 (1.04–3.91)

0.041

Acute GVHD grades III–IV

2.37 (1.29–3.55)

0.006

  1. Multivariate analyses were based on the subdistribution regression model of Fine and Gray.
  2. HR hazard ratio, CI confidence interval.
  3. aHazard ratios were adjusted for patient age and gender, type of transplantation, acute GVHD III–IV and antifungal prophylaxis. Only the variables remaining significant after adjustment are shown. The P-values are two-sided and no corrections for multiple testing were performed.
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