Fig. 3: Scope of amines. | Nature Communications

Fig. 3: Scope of amines.

From: Ni-catalyzed hydroaminoalkylation of alkynes with amines

Fig. 3

Reaction conditions: 1 (0.20 mmol), 2a (0.22 mmol), toluene (2.0 mL) under N2 for 1−12 h; yield of isolated products. *Ni(cod)2 (10 mol%), IPr·HCl (10 mol%), PCy3 (10 mol%), tBuOK (12 mol%) at 110 °C. Ni(cod)2 (20 mol%), IMes·HCl (20 mol%), PCy3 (20 mol%), tBuOK (22 mol%) at 130 °C. Ts = tolylsulfonyl.

Back to article page