Fig. 1: Structural representation of the different classes of cellulases characterized in this study.
From: Physical constraints and functional plasticity of cellulases
a Surface representation of the six different glycoside hydrolase (GH) families (exemplified by the PDB ID: 4C4C53 (GH7), 1QK255 (GH6), 1H8V56 (GH12), 4ENG58 (GH45), 3QR357 (GH5)). b Structure of two GH7 cellulases with different modes of action in complex with cellononaose. A cellobiohydrolase (CBH) with a tunnel-shaped catalytic domain (PDB: 4C4C) and an endoglucanase (EG) with an open catalytic cleft (PDB: 1EG154). c Illustration of a GH7 CBH in complex with a cellulose fiber. The enzyme is modular with a catalytic domain (CD) and a carbohydrate-binding module (CBM) connected by a flexible linker. All structures were visualized using PyMOL71.
