Fig. 3: Structure comparison between C9orf72:ARF1-SMCR8:WDR41 with other GAP:small GTPases.
From: Structural basis for the ARF GAP activity and specificity of the C9orf72 complex

a Structure comparison between C9orf72:ARF1-SMCR8:WDR41 (left) with ASAP3:ARF6 (middle) and TBC1D20:RAB1B (right). The small GTPases are shown in the same orientations. b Close-up views of the nucleotide-binding sites with catalytic Arginine finger residues pointing to the active sites.