Fig. 1: Identification and characterization of a Tcf21-expressing interstitial somatic cell in the adult testis. | Nature Communications

Fig. 1: Identification and characterization of a Tcf21-expressing interstitial somatic cell in the adult testis.

From: TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

Fig. 1

A Visualization of 6 somatic cell types in PC space. Data reprocessed from Green et al.13. Note somatic cell populations were enriched using a combination of cell surface markers or transgenic lines, therefore cell frequencies in PCA plot are not representative of in vivo. B Heatmap of dissimilarity matrix of somatic cell types illustrates high similarity for the Tcf21+ interstitial population with 3 somatic cell types—myoid, Leydig, and endothelial cells. Gray scale indicates Euclidean distance. C Violin plots of representative markers for endothelial, myoid, Tcf21+ interstitial population, and Leydig cells. D Heatmap of differentially expressed markers for each of the 4 closely related somatic cell types—endothelial, myoid, Tcf21+ interstitial population, and Leydig cells.

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