Fig. 3: Relationship between two protein family scores (core AD and IL6) and cognitive decline in participants with normal cognition (NC).
From: Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease
NC participants with high core AD scores had earlier conversion to diagnosis of mild cognitive impairment (MCI; a, p = 0.021) or global clinical dementia rating score (CDR) of 0.5 (b p = 0.023), but further stratification according to IL6 score did not further refine long-term cognitive outcomes. Sample size in the NC cohort was 109 after excluding two participants with very rapid decline from NC to dementia. Source data are provided as a Source Data file.
