Fig. 6: XyG enzymatic breakdown and the role of released products in the metabolism and virulence of X. citri.

Representation of the pathogen-host cell interface highlighting how XyG is progressively depolymerized by Xanthomonas enzymes and internalized by transmembrane transporters. In this bacterium, monosaccharides released from XyG induce the expression of multiple genes, including the T3SS machinery via mechanisms suggested based on transcriptional data and literature54,55,56 (details in Supplementary Fig. 28, and Supplementary Table 1). T3, Type III; T3SS, Type III secretion system; TBDTs, TonB-dependent transporters; MFS, major facilitator superfamily transporter; G6P, D-glucose-6-phosphate; F6P, D-fructose-6-phosphate, GA3P, D-glyceraldehyde 3-phosphate; Xul, D-xylulose; X5P, D-xylulose 5-phosphate; and TCA, Tricarboxylic Acid cycle.