Fig. 3: TMPRSS2 is expressed at higher levels in the male lung compared to female lung. | Nature Communications

Fig. 3: TMPRSS2 is expressed at higher levels in the male lung compared to female lung.

From: The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells

Fig. 3

The GTEx dataset40 was interrogated and expression of AR and TMPRSS2 investigated in lung tissue and dichotomised by gender, M = male (N = 220), F = female (N = 355). Box and whiskers: the centre line represents the median, the box represents the 25th and 75th percentile and the bars represent the min and max values. One-tailed t-test, *p = 0.0403.

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