Fig. 5: Biocompatibility of the encapsulated I-TENG.
From: Self-rechargeable cardiac pacemaker system with triboelectric nanogenerators
a Schematic image of the implanted device under the subcutaneous fat of the mongrel model. b Masson’s trichrome stain results of (i) no inflammatory cells and scanty amount of perivascular fibrosis observed in normal muscle; (ii) prominent fibrosis and a mild inflammatory response around the encapsulated device; and (iii) similar fibrosis and inflammatory response around a commercial medical device. Red, white, and blue represent normal muscle, fat, and infection, respectively. Yellow arrow was analyzed by randomly selecting each of five groups in sections of tissue implanted. scale bar, 1 mm. Inset figures scale bar, 50 µm. The Masson’s trichrome stain results randomly selected five groups of three different conditions. c Comparison of fibrosis area (%) of (i) normal muscles, (ii) muscle tissue around the encapsulated device, and (iii) muscle surrounding the commercial medical device, determined using ImageJ software. n = 5, p value = 0.0002, one-way ANOVA. Error bars correspond to standard deviations.
