Fig. 8: Schematic of the methodological workflow.
From: A generative network model of neurodevelopmental diversity in structural brain organization
The basic workflow involved (i) Recruitment of the CALM cohort, a heterogeneous referred sample from the East of England (UK) with wide inclusion criteria; (ii) MRI diffusion tensor imaging; (iii) Estimation of structural connectivity within the Desikan–Killiany parcellation; (iv) Binarization of the connectome; (v) Initial run of the GNM for all 13 generative rules as outlined in Supplementary Table 1; (vi) More specific run of the homophily “matching” GNM in the narrow parameter window; (vii) Further analysis of simulations in terms of spatial embedding, parameter associations and variability; (viii) Combination of Allen Human Brain Atlas data and the generative model findings.
