Fig. 1: Integrated RNA extraction and detection with the OIL-TAS assay. | Nature Communications

Fig. 1: Integrated RNA extraction and detection with the OIL-TAS assay.

From: Oil immersed lossless total analysis system for integrated RNA extraction and detection of SARS-CoV-2

Fig. 1

a Schematic depicting the design and essential components of the OIL-TAS. b Side view cartoon illustrating the operation principle of OIL-TAS sample extraction. Owing to the exclusive liquid-repellent (ELR) nature of the device surface, droplets appear spherical which minimizes contact with the device surface and hence biofouling-associated sample loss. c Images of a single unit of the OIL-TAS device before and after extraction. Each unit includes a large sample well for sample lysis and binding, followed by two washing wells and a detection well. Interconnecting the wells are oil-filled extraction channels. Wells are filled with droplets of food coloring for visualization.

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