Table 1 Genes that share a strong Boolean implication relationship with PRKAB1 on the major continuum paths in IBD (related to Fig. 3C, D).
1A. Epithelial Mesenchymal Transition (EMT) Continuum | |||
|---|---|---|---|
CCDC88A | IL17B | OCLN | SIRT1 |
CDH1 | IL23A | PARD3 | SIRT6 |
CLDN2 | IL6 | PML | SMAD7 |
CXCL10 | IL6 | PPARG | SNAI1 |
ELMO1 | ITGA4 | PPARGC1A | SNAI2 |
F11R | ITGB1 | PRKAB1 | SPHK1 |
HIF1A | ITGB7 | PRKCQ | TLR2 |
HMOX1 | JAK1 | RIPK2 | TLR4 |
IL12A | MADCAM1 | S1PR1 | VIM |
IL17A | NOD2 | S1PR5 | |
1B. Healing – Fibrosis Continuum | |||
|---|---|---|---|
PRKAB1 | MRC1 | MMP3 | S1PR1 |
PPARG | IL33 | MMP9 | S1PR5 |
PPP1CA | IL6 | MMP12 | JAK1 |
PPARGC1A | CCL2 | MMP13 | SMAD7 |
CCDC88A | TNF | MMP14 | IL17A |
PRKCQ | COL1A1 | IL11 | IL17B |
ACTA2 | TIMP1 | ITGA4 | IL12A |
TGFB1 | TIMP2 | ITGB1 | IL23A |
IL10 | MMP1 | ITGB7 | IL6 |
IL1B | MMP2 | MADCAM1 | RIPK2 |
