Fig. 1: Manhattan plots showing trans-ancestry GWAS results for ALT and AST. | Nature Communications

Fig. 1: Manhattan plots showing trans-ancestry GWAS results for ALT and AST.

From: GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms

Fig. 1

Red dots indicate lead variants for shared signals between the two GWAS; for clarity, the shared signals are marked only once, on the plot for the GWAS in which the more significant association is detected. Cis-pQTLs (at GPT and GOT2) are labeled in blue. Loci with shared signals are labeled (for clarity, only when p < 10−25 and only on the GWAS for which the association is most significant). Loci previously reported to associate with both ALT and AST are named in bold. SLC30A10, the main topic of this report, is labeled in red on both plots. Source data for this figure are available from NHGRI-EBI GWAS catalog accession GCST90013663 and GCST90013664.

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