Fig. 3: Structural characterization of identified self-assembling pentapeptides.
From: Rapid discovery of self-assembling peptides with one-bead one-compound peptide library
a–c TEM images of FFVDF, YFTEF, and PFTTR pentapeptides (30 mM in H2O). Insets: photographs of the suspension, gel, and solution. The scale bar is 200 nm. d FT-IR absorption spectra in the amide I region of pentapeptides FFVDF, YFTEF, and PFTTR (30 mM in H2O); narrowing and red-shifting of the amide modes of FFVDF and YFTEF indicate the presence of well-ordered assemblies for these peptides. e The transmittance spectra of FFVDF, YFTEF, and PFTTR at a concentration of 20 µM. f X-ray diffraction powder pattern of FFVDF nanofibrils. g Bright-field TEM image of nanofibrils self-assembled from FFVDF (30 μM in H2O with 1% DMSO). The scale bar is 200 nm. h Selected-area electron diffraction (SAED) pattern of the nanofibers corresponding to the part of BF image in (g). i ab-, ac-, bc-plane projections of the proposed molecular packing model of the nanofibers based on SAED and powder X-ray diffraction results.
