Fig. 5: Enrichment analysis of CTC miRNAs and miRNA candidates. | Nature Communications

Fig. 5: Enrichment analysis of CTC miRNAs and miRNA candidates.

From: Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells

Fig. 5

a–f Top enriched organs, pathway categories, and cellular locations. Each plot shows the computed running sum (blue), running sums of random permutations (background), and the FDR adjusted P value. Exact p values were computed by the gene set enrichment analysis implementation of miEAA for each enrichment and FDR adjusted, separately for each database. g Pileup plot obtained from miRCarta for one of the overlapping miRNA candidates. The bars are colored according to the experiments the reads were contributed from. The expression is shown as reads per million mapped (RPMM). h Distribution of the read proportion supplied by each experiment that detected this miRNA.

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