Fig. 5: B cells are similar between serum DSA-positive and negative patients.
From: Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
a–e t-SNE plots of the integrated data of the two cohorts. Shape indicates tissue source, and color indicates patients (a), Ig class-switch state (b), PRDM1 expression (c), clusters assigned by Seurat (d), and serum DSA positivity (e). f Volcano plots showing differential gene expression in non-plasma B cells, comparing DSA-positive and negative patients. Shown on the right side of the plots are genes upregulated in B cells from DSA-positive patients. Genes above the significance threshold were colored in red, and names of top-hit genes were labeled.
