Fig. 5: Complex models of the response regulators DrRR and AtRR1 and their interacting DHp domains.

a–c Model of the DrBphP/DrRR complex. d–f Model of the Agp1/AtRR1 complex. The overall structure of the complexes are shown in panels (a) and (d), detailed interactions around the active site in panels (b, c) and (e, f). The orientation of the complex is flipped by 180° in panels (c) and (f). Representative structural snapshots from the MD simulations are shown. The surrounding water box with Na+ and Cl− ions is omitted for clarity, and only one monomer of the response regulator dimer is shown.