Fig. 6: The expression of miR200s and miR21 was increased in cystic renal epithelial cells and tissues. | Nature Communications

Fig. 6: The expression of miR200s and miR21 was increased in cystic renal epithelial cells and tissues.

From: Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease

Fig. 6

a qRT-PCR analysis of the expression of miR200b, miR200c, and miR429 in PH2 and PN24 cells. All data were analyzed from three experiments. b qRT-PCR analysis of the expression of miR200b, miR200c, and miR429 in kidneys of WT and Pkd1RC/RC mice. All data were analyzed from 4 experiments. c qRT-PCR analysis of the expression of miR200b, miR200c and miR429 in kidneys of WT and Pkd1flox/flox:Pkhd1-Cre mice. All data were analyzed from three experiments. d qRT-PCR analysis of the expression of miR200b, miR200c and miR429 in 1 mg of EVs/exosomes derived from PH2 and PN24 cells. All data were analyzed from five experiments. e qRT-PCR analysis of the expression of miR200b, miR200c, and miR429 in 1 mg EVs/exosomes derived from Pkd1 wild-type and null MEK cells. All data were analyzed from five experiments. qRT-PCR analysis of the expression of miR21 in PH2 and PN24 cells (f) and in kidneys of WT and Pkd1RC/RC mice (g) as well as in kidneys of WT and Pkd1flox/flox:Pkhd1-Cre mice (h). i qRT-PCR analysis of the expression of miR21 in 1 mg of EVs/exosomes derived from the PH2 and PN24 cells. All data were analyzed from 3 to 5 experiments. j qRT-PCR analysis of the expression of miR21 in 1 mg of EVs/exosomes derived from Pkd1 wild-type and null MEK cells. All data were analyzed from five experiments. All statistical data are represented as mean ± SEM, and p-values are calculated by unpaired Student’s t-test.

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