Fig. 3: Splicing TWAS.
From: Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization
A Manhattan plot of genes associated via multiple tissue spTWAS. Each data point represents a splice site grouped by chromosome (x-axis) and lowest p value (y-axis) of the splice site for each gene across significant tissues. The annotated genes to the splice site are labeled. Significant splice sites are shown as pink diamonds. B Distribution of splice sites across significant site-tissue pairs. The genes annotated to splice sites are grouped based on chromosomes (y-axis) and respective tissues (x-axis).
