Fig. 4: Cross-talk between mitochondria and ER/SR facilitates mitochondrial calcium cycling. | Nature Communications

Fig. 4: Cross-talk between mitochondria and ER/SR facilitates mitochondrial calcium cycling.

From: Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis

Fig. 4

a Representative co-immunoprecipitation image from a cardiac ventricular sample of 8-week-old mice (n = 3) in WT and KO (Input—non-IP sample; IgG—control antibody; IP—VDAC2 protein pull-down); b Representative proximity ligation assay image for VDAC2–SERCA2 and VDAC2–NCX1 interaction in 8-week-old mice (scale bar, 10 μm) (n = 3); c Representative immunofluorescence image from 16-week-old mice heart (scale bar, 10 μm) (n = 3).

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