Fig. 4: Viruses in complex membrane compartments (CMCs).
From: Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
A A tomographic slice of a CMC in cell lamella depicting convoluted membranes containing virus particles (boxed area). B Detailed tomogram slice of spikeless viruses from the boxed area in A. C, D Consecutive tomographic slices of the same CMC separated by 140 nm, containing viruses (black and blue boxed areas). E, F Detailed tomogram slice of viruses with a few postfusion spikes (yellow arrows) from boxed areas in C, D. G, H Detailed tomogram slice of viruses protected by single membrane vesicles (SMVs) harboring prefusion spikes (red arrows) from blue boxed areas in D. Scale bars are 100 nm in A, C, D; 50 nm in B, E–H.
