Fig. 5: ΔAIL p300340–2094 interacts ‘in trans’ in solution. | Nature Communications

Fig. 5: ΔAIL p300340–2094 interacts ‘in trans’ in solution.

From: Nuclear condensates of p300 formed though the structured catalytic core can act as a storage pool of p300 with reduced HAT activity

Fig. 5

a Small angle X-ray scattering (SAXS) data collected for WT (upper panel) and ΔAIL (lower panel) p300340–2094 upon addition of acetyl-CoA at indicated time points including 0 min (blue) and 90 min (orange). SAXS intensity (left), Rg plots (middle), and P(r) functions (right) determined from the experimental scattering data were shown. b Schematics of the WT and ΔAIL p300BRPH intramolecular and intermolecular interactions between BD and acetylated lysines.

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