Table 1 Sample description.

From: Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children

Index

Age

Gender

Ethnicity

Comorbidities

Immunosuppressive

MIS-C

M1

0–5

Male

Hispanic

None

None

M2

6–11

Female

Hispanic

None

None

M3

12–17

Male

Black

Asthma

None

M4

0–5

Female

Hispanic

None

None

M5

18–23

Male

Hispanic

Asthma

None

M6

12–17

Male

Hispanic

Appendicitis

None

M7

12–17

Female

Black

MDD, PTSD

None

M8

6–11

Female

Hispanic

None

None

Pediatric COVID-19

C1

6–11

Female

Hispanic

B-cell ALL

Chemotherapy

C2

18–23

Male

Hispanic

Asthma

None

C3

0–5

Male

Hispanic

Autoimmune Anemia

Steroids

C4

18–23

Female

Not Reported

Pineoblastoma

Chemotherapy

C5

18–23

Male

Hispanic

B-cell ALL

Chemotherapy

C6

6–11

Male

White

Gastrochisis

Tacrolimus

C7

12–17

Male

Black

IBD

Infliximab

Healthy controls

H1

24–29

Female

Asian

None

None

H2

35–40

Male

White

None

None

H3

24–29

Female

White

None

None

H4

35–40

Female

White

None

None

  1. Demographic and clinical variables for the MIS-C cases (N = 8), pediatric COVID-19 cases (N = 7), and healthy controls (N = 4). Index column refers to the individual identifiers. Age is presented in years. Sex, ethnicity, and comorbidities are as reported in the electronic medical record. Immunosuppressants indicate the usage of chronic immunosuppressive therapies for any indication. Further clinical data can be found in Supplementary Data 13.
  2. MDD major depressive disorder, PTSD post-traumatic stress disorder, ALL acute lymphoblastic leukemia, IBD inflammatory bowel disease.